搜索 - 科创

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克莱森－施密特缩合反应　为两种不同的醛或酮在强碱作用下发生的反应，一般指芳香醛与脂肪族醛或酮的反应。脂肪族烯醇负离子进攻芳香醛的羰基碳原子，随即失水得到一种与芳香环共轭的α,β－不饱和醛或酮。　　

目标物质4-(二甲胺基)苄腈的制备多篇综述推荐的由给电子基取代的芳香醛制备对应芳香腈的推荐条件是：I2，浓氨水，60℃，3h，然后用亚硫酸钠除去过剩碘。

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