%7B%22allCategories%22%3A%5B%7B%22_id%22%3A16%2C%22cid%22%3Anull%2C%22defaultNode%22%3A%22default%22%2C%22nodeName%22%3A%22%E9%83%BD%E4%B8%8D%E6%98%AF%22%2C%22warning%22%3A%22%E8%AF%B7%E5%87%86%E7%A1%AE%E9%80%89%E6%8B%A9%EF%BC%8C%E5%88%87%E5%8B%BF%E4%B9%B1%E9%80%89%EF%BC%8C%E4%B8%8D%E7%9F%A5%E9%81%93%E6%80%8E%E4%B9%88%E9%80%89%E5%B0%B1%E9%80%89%E9%83%BD%E4%B8%8D%E6%98%AF%E3%80%82%22%2C%22threadWarning%22%3A%22%22%2C%22description%22%3A%22%E5%A6%82%E6%9E%9C%E5%B1%9E%E4%BA%8E%E7%89%B9%E6%AE%8A%E8%AF%9D%E9%A2%98%EF%BC%8C%E5%BF%85%E9%A1%BB%E5%A3%B0%E6%98%8E%E3%80%82%E5%A6%82%E6%9E%9C%E4%B8%8D%E5%B1%9E%E4%BA%8E%E7%89%B9%E6%AE%8A%E8%AF%9D%E9%A2%98%EF%BC%8C%E9%80%89%E6%8B%A9%E2%80%9C%E4%BB%A5%E4%B8%8A%E9%83%BD%E4%B8%8D%E6%98%AF%E2%80%9D%E3%80%82%22%2C%22icon%22%3A%22%22%2C%22order%22%3A0%2C%22disabled%22%3Afalse%2C%22name%22%3A%22%E7%89%B9%E6%AE%8A%E8%AF%9D%E9%A2%98%E5%A3%B0%E6%98%8E%22%2C%22source%22%3A%22article%22%2C%22toc%22%3A%222022-12-30T15%3A45%3A03.487Z%22%2C%22__v%22%3A0%2C%22id%22%3A%2216%22%7D%2C%7B%22_id%22%3A17%2C%22cid%22%3A16%2C%22defaultNode%22%3A%22none%22%2C%22nodeName%22%3A%22%E9%BB%98%E8%AE%A4%22%2C%22warning%22%3A%22%E6%97%B6%E4%BA%8B%E6%94%BF%E6%B2%BB%E7%AD%89%E8%AF%9D%E9%A2%98%EF%BC%8C%E5%BF%85%E9%A1%BB%E9%80%89%E6%8B%A9%E6%9C%AC%E7%B1%BB%E3%80%82%22%2C%22threadWarning%22%3A%22%E5%8F%91%E8%A1%A8%E5%92%8C%E5%8F%82%E4%B8%8E%E6%97%B6%E4%BA%8B%E6%97%B6%E6%94%BF%E8%AF%9D%E9%A2%98%EF%BC%8C%E8%AF%B7%E4%B8%A5%E6%A0%BC%E5%B1%80%E9%99%90%E4%BA%8E%E5%AD%A6%E6%9C%AF%E8%8C%83%E7%95%B4%EF%BC%8C%E4%B8%A5%E9%98%B2%E6%BC%94%E5%8F%98%E4%B8%BA%E9%94%AE%E6%94%BF%E5%92%8C%E6%84%8F%E8%AF%86%E5%BD%A2%E6%80%81%E4%BA%89%E8%AE%BA%E3%80%82%22%2C%22description%22%3A%22%E8%AF%B7%E5%87%86%E7%A1%AE%E9%80%89%E6%8B%A9%EF%BC%8C%E4%B8%8D%E8%A6%81%E4%B9%B1%E9%80%89%E3%80%82%22%2C%22icon%22%3A%22%22%2C%22order%22%3A1%2C%22disabled%22%3Afalse%2C%22name%22%3A%22%E6%97%B6%E4%BA%8B%E6%97%B6%E6%94%BF%22%2C%22source%22%3A%22article%22%2C%22toc%22%3A%222022-12-30T15%3A47%3A34.565Z%22%2C%22__v%22%3A0%2C%22id%22%3A%2217%22%7D%2C%7B%22_id%22%3A18%2C%22cid%22%3A16%2C%22defaultNode%22%3A%22none%22%2C%22nodeName%22%3A%22%E9%BB%98%E8%AE%A4%22%2C%22warning%22%3A%22%E6%8F%90%E9%97%AE%E6%B1%82%E5%8A%A9%E7%B1%BB%E8%AF%9D%E9%A2%98%E5%BF%85%E9%A1%BB%E9%80%89%E6%8B%A9%E6%9C%AC%E7%B1%BB%E3%80%82%22%2C%22threadWarning%22%3A%22%E6%8F%90%E9%97%AE%E6%B1%82%E5%8A%A9%E7%B1%BB%E8%AF%9D%E9%A2%98%E5%BF%85%E9%A1%BB%E6%8F%90%E4%BE%9B%E5%85%85%E8%B6%B3%E7%9A%84%E5%B7%B2%E7%9F%A5%E6%9D%A1%E4%BB%B6%EF%BC%8C%E4%BB%8B%E7%BB%8D%E4%B8%BA%E4%BA%86%E8%A7%A3%E5%86%B3%E9%97%AE%E9%A2%98%E5%B7%B2%E7%BB%8F%E5%81%9A%E7%9A%84%E5%B7%A5%E4%BD%9C%E3%80%82%E5%87%A1%E5%8F%AF%E4%BB%A5%E9%80%9A%E8%BF%87%E7%AE%80%E5%8D%95%E6%90%9C%E7%B4%A2%E6%88%96%E6%9F%A5%E9%98%85%E6%95%99%E7%A7%91%E4%B9%A6%E8%A7%A3%E5%86%B3%E7%9A%84%E9%97%AE%E9%A2%98%EF%BC%8C%E4%B8%8D%E5%BA%94%E6%8F%90%E9%97%AE%E6%B1%82%E5%8A%A9%E3%80%82%E8%BF%9E%E7%BB%AD%E5%8F%91%E5%B8%83%E6%8F%90%E9%97%AE%E6%B1%82%E5%8A%A9%E3%80%81%E6%87%92%E6%83%B0%E5%9E%8B%E6%8F%90%E9%97%AE%E3%80%81%E4%B8%8A%E5%B8%9D%E5%BC%8F%E6%8F%90%E9%97%AE%E7%AD%89%EF%BC%8C%E5%B0%86%E5%8F%97%E5%88%B0%E5%A4%84%E7%BD%9A%E7%9B%B4%E8%87%B3%E5%B0%81%E5%8F%B7%E3%80%82%22%2C%22description%22%3A%22%E8%AF%B7%E5%87%86%E7%A1%AE%E9%80%89%E6%8B%A9%EF%BC%8C%E4%B8%8D%E8%A6%81%E4%B9%B1%E9%80%89%E3%80%82%22%2C%22icon%22%3A%22%22%2C%22order%22%3A0%2C%22disabled%22%3Afalse%2C%22name%22%3A%22%E6%B1%82%E5%8A%A9%E6%8F%90%E9%97%AE%22%2C%22source%22%3A%22article%22%2C%22toc%22%3A%222022-12-30T15%3A49%3A30.585Z%22%2C%22__v%22%3A0%2C%22id%22%3A%2218%22%7D%2C%7B%22_id%22%3A19%2C%22cid%22%3Anull%2C%22defaultNode%22%3A%22default%22%2C%22nodeName%22%3A%22%E4%B8%8D%E5%8C%85%E5%90%AB%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%E5%86%85%E5%AE%B9%22%2C%22warning%22%3A%22%E5%A6%82%E6%9E%9C%E5%8C%85%E5%90%AB%E5%AE%A3%E4%BC%A0%E3%80%81%E6%8E%A8%E5%B9%BF%E6%88%96%E5%95%86%E4%B8%9A%E5%86%85%E5%AE%B9%EF%BC%8C%E8%AF%B7%E5%A3%B0%E6%98%8E%22%2C%22threadWarning%22%3A%22%22%2C%22description%22%3A%22%E5%A6%82%E5%8C%85%E5%90%AB%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%E5%86%85%E5%AE%B9%EF%BC%8C%E5%BA%94%E5%A3%B0%E6%98%8E%22%2C%22icon%22%3A%22%22%2C%22order%22%3A1%2C%22disabled%22%3Afalse%2C%22name%22%3A%22%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%22%2C%22source%22%3A%22article%22%2C%22toc%22%3A%222022-12-30T15%3A54%3A40.337Z%22%2C%22__v%22%3A0%2C%22id%22%3A%2219%22%7D%2C%7B%22_id%22%3A20%2C%22cid%22%3A19%2C%22defaultNode%22%3A%22none%22%2C%22nodeName%22%3A%22%E9%BB%98%E8%AE%A4%22%2C%22warning%22%3A%22%E5%A6%82%E6%9E%9C%E5%8C%85%E5%90%AB%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%E5%86%85%E5%AE%B9%EF%BC%8C%E5%BF%85%E9%A1%BB%E5%A3%B0%E6%98%8E%22%2C%22threadWarning%22%3A%22%E5%8F%AF%E8%83%BD%E5%90%AB%E6%9C%89%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%E6%88%96%E5%95%86%E4%B8%9A%E5%86%85%E5%AE%B9%EF%BC%8C%E8%AF%B7%E8%B0%A8%E6%85%8E%E8%AF%86%E5%88%AB%E3%80%82%22%2C%22description%22%3A%22%22%2C%22icon%22%3A%22%22%2C%22order%22%3A2%2C%22disabled%22%3Afalse%2C%22name%22%3A%22%E5%8C%85%E5%90%AB%E5%AE%A3%E4%BC%A0%E6%8E%A8%E5%B9%BF%E5%86%85%E5%AE%B9%22%2C%22source%22%3A%22article%22%2C%22toc%22%3A%222022-12-30T16%3A02%3A38.807Z%22%2C%22__v%22%3A0%2C%22id%22%3A%2220%22%7D%5D%2C%22comments%22%3A%5B%5D%2C%22article%22%3A%7B%22_id%22%3A%22610odz%22%2C%22toc%22%3A%222024-11-06T06%3A06%3A48.621Z%22%2C%22tlm%22%3A%222024-11-06T07%3A39%3A23.816Z%22%2C%22uid%22%3A%22105575%22%2C%22did%22%3A897714%2C%22digest%22%3Afalse%2C%22digestTime%22%3Anull%2C%22status%22%3A%22normal%22%2C%22hasDraft%22%3Afalse%2C%22source%22%3A%22column%22%2C%22sid%22%3A%22%22%2C%22hits%22%3A462%2C%22voteUp%22%3A0%2C%22voteDown%22%3A0%2C%22comment%22%3A0%2C%22references%22%3A%5B%5D%2C%22tcId%22%3A%5B%5D%2C%22__v%22%3A0%2C%22id%22%3A%22610odz%22%2C%22xsf%22%3A%5B%5D%2C%22kcb%22%3A%5B%5D%2C%22reason%22%3A%22%22%2C%22document%22%3A%7B%22references%22%3A%5B%5D%2C%22description%22%3A%22%22%2C%22declaration%22%3A%22%22%2C%22_id%22%3A901399%2C%22did%22%3A897714%2C%22type%22%3A%22stable%22%2C%22quoteDid%22%3A%22%22%2C%22status%22%3A%22normal%22%2C%22uid%22%3A%22105575%22%2C%22dt%22%3A%222024-11-06T06%3A06%3A48.621Z%22%2C%22toc%22%3A%222024-11-06T06%3A06%3A48.621Z%22%2C%22tlm%22%3Anull%2C%22cover%22%3A%22%22%2C%22title%22%3A%22%E5%88%B6%E5%A4%87%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8%22%2C%22files%22%3A%5B%5D%2C%22content%22%3A%22%3Cp%3E%E9%A6%96%E5%85%88%E6%90%AD%E5%BB%BA%E5%8F%8D%E5%BA%94%E8%A3%85%E7%BD%AE%3Cbr%3E%3C%2Fp%3E%3Cp%3Ea.%E7%94%B5%E7%83%AD%E5%A5%97%EF%BC%8C500ml%E7%9A%84%E5%9C%86%E5%BA%95%E7%83%A7%E7%93%B6%E5%92%8C%E9%80%9A%E6%B0%B4%E5%86%B7%E5%87%9D%E7%AE%A1%E6%90%AD%E5%BB%BA%E6%88%90%E4%B8%80%E4%B8%AA%E5%9B%9E%E6%B5%81%E5%86%B7%E5%87%9D%E8%A3%85%E7%BD%AE%3C%2Fp%3E%3Cp%3Eb.%E7%A7%B0%E9%87%8F%E5%8F%8D%E5%BA%94%E7%89%A9%E3%80%8274g%E9%82%BB%E8%8B%AF%E4%BA%8C%E7%94%B2%E9%85%B8%E9%85%90(0.5mol)%E4%B8%8E15g%E8%84%B2(0.25mol)%E6%B7%B7%E5%90%88%E5%90%8E%E5%8A%A0%E5%85%A5%E5%9C%86%E5%BA%95%E7%83%A7%E7%93%B6%3C%2Fp%3E%3Cp%3Ec.%E5%86%B7%E5%87%9D%E7%AE%A1%E9%80%9A%E5%85%A5%E5%86%B7%E5%87%9D%E6%B0%B4%E5%90%8E%E5%BC%80%E5%A7%8B%E5%8A%A0%E7%83%AD%E8%87%B3%E6%B7%B7%E5%90%88%E7%89%A9%E7%86%94%E8%9E%8D%EF%BC%8C%E6%AD%A4%E6%97%B6%E4%BC%9A%E6%94%BE%E5%87%BA%E4%BA%8C%E6%B0%A7%E5%8C%96%E7%A2%B3%EF%BC%8C%E6%B3%A8%E6%84%8F%E6%8E%A7%E6%B8%A9%E9%98%B2%E6%AD%A2%E5%8F%8D%E5%BA%94%E5%A4%B1%E6%8E%A7%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361457%5C%22%20src%3D%5C%22%2Fr%2F361457%5C%22%3Eps%3A%E8%BF%99%E6%98%AF250ml%E7%9A%84%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361463%5C%22%20src%3D%5C%22%2Fr%2F361463%5C%22%3E%3C%2Fp%3E%3Cp%3Ed.%E5%BD%93%E6%B7%B7%E5%90%88%E7%89%A9%E8%86%A8%E8%83%80%E5%90%8E%E5%8F%8D%E5%BA%94%E5%AE%8C%E6%88%90%EF%BC%8C%E5%86%B7%E5%8D%B4%E5%90%8E%E5%8A%A0%E5%85%A5100ml%E7%83%AD%E6%B0%B4%E5%8A%A0%E7%83%AD%E8%87%B3%E6%B2%B8%E8%85%BE%E8%BF%87%E6%BB%A4%EF%BC%8C%E5%B9%B2%E7%87%A5%E5%90%8E%E5%8D%B3%E7%BA%AF%E5%87%80%E7%9A%84%E9%82%BB%E8%8B%AF%E4%BA%8C%E7%94%B2%E9%85%B0%E4%BA%9A%E8%83%BA(%E8%AE%B0%E4%B8%BA%CE%B1)%EF%BC%8C%E5%85%B162g%EF%BC%8C%E4%BA%A7%E7%8E%8784%25%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361458%5C%22%20src%3D%5C%22%2Fr%2F361458%5C%22%3E%3C%2Fp%3E%3Cp%3E%3C%2Fp%3E%3Cp%3Ee.%E9%85%8D%E7%BD%AENaOH(aq)%E9%80%82%E9%87%8F(%E5%85%B1%E5%90%AB%E6%9C%89NaOH%2033g)%EF%BC%8C%E5%8A%A0%E5%85%A5%E6%89%80%E6%9C%89%E7%9A%84%CE%B1%EF%BC%8C%E7%AD%89%E5%BE%85%E6%BA%B6%E6%B6%B2%E6%BE%84%E6%B8%85%E3%80%82%3C%2Fp%3E%3Cp%3Ef.%E5%87%86%E5%A4%87300mlNaClO(aq)%E5%86%B7%E5%8D%B4%E8%87%B35%E2%84%83%3C%2Fp%3E%3Cp%3Eg.%E6%90%AD%E5%BB%BA%E5%86%B0%E6%B0%B4%E6%B5%B4%E5%86%B7%E5%8D%B4e%E7%9A%84%E6%BA%B6%E6%B6%B2%E9%9A%8F%E5%90%8E%E6%85%A2%E6%85%A2%E6%BB%B4%E5%85%A5NaClO(aq)%E3%80%82%E6%AD%A4%E6%97%B6%E5%8F%91%E7%94%9F%E9%9C%8D%E5%A4%AB%E6%9B%BC%E9%87%8D%E6%8E%92%E3%80%82%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361464%5C%22%20src%3D%5C%22%2Fr%2F361464%5C%22%3E%3C%2Fp%3E%3Cp%3E%E5%8F%8D%E5%BA%94%E6%B6%B2%E9%A2%9C%E8%89%B2%E5%8F%98%E6%B7%B1%EF%BC%8C%E8%BF%99%E6%98%AF%E5%89%AF%E5%8F%8D%E5%BA%94%E3%80%82%3C%2Fp%3E%3Cp%3E%E5%90%8C%E6%97%B6%E7%94%9F%E6%88%90CO%E2%82%82%E6%94%BE%E5%87%BA%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361460%5C%22%20src%3D%5C%22%2Fr%2F361460%5C%22%3E%3C%2Fp%3E%3Cp%3Eh.%E6%BB%B4%E5%8A%A0%E5%AE%8C%E6%88%90%E5%90%8E%EF%BC%8C%E5%8A%A0%E5%85%A5%E7%A8%80%E7%A1%AB%E9%85%B8%E8%B0%83ph%E8%87%B34%E5%B7%A6%E5%8F%B3(%E6%B3%A8%E6%84%8FCO%E2%82%82%E6%94%BE%E5%87%BA)%EF%BC%8C%E5%8D%B3%E6%9C%89%E6%A3%95%E8%89%B2%E6%B2%89%E6%B7%80%E4%BA%A7%E7%94%9F%EF%BC%8C%E6%8A%BD%E6%BB%A4%E8%8E%B7%E5%BE%97%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8%EF%BC%8C%E4%BA%A7%E7%89%A9%E5%BA%94%E6%98%AF%E6%97%A0%E6%B0%B4%E7%9A%84%EF%BC%8C%E4%BD%9C%E8%80%85%E7%94%A850%25%E7%9A%84EtOH%E9%87%8D%E7%BB%93%E6%99%B6%E4%BA%86%E4%B8%80%E6%AC%A1%E3%80%82%E4%BA%A7%E5%93%81%E5%B9%B2%E7%87%A5%E5%90%8E30g%EF%BC%8C%E4%BA%A7%E7%8E%8751%25%3C%2Fp%3E%3Cp%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361459%5C%22%20src%3D%5C%22%2Fr%2F361459%5C%22%3E%3Cimg%20data-tag%3D%5C%22nkcsource%5C%22%20data-type%3D%5C%22picture%5C%22%20data-id%3D%5C%22361462%5C%22%20src%3D%5C%22%2Fr%2F361462%5C%22%3E%3C%2Fp%3E%3Cp%3E(ps%3A%E4%BD%9C%E8%80%85%E5%B0%86%E4%BC%9A%E7%94%A8%E4%BA%8E%E5%90%88%E6%88%90%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8%E7%94%B2%E9%85%AF%EF%BC%8C%E6%95%85%E6%97%A0%E9%9C%80%E9%9D%9E%E5%B8%B8%E7%BA%AF%E5%87%80)%3C%2Fp%3E%3Cp%3E%3C%2Fp%3E%22%2C%22keywordsEN%22%3A%5B%5D%2C%22keywords%22%3A%5B%22%E6%9C%89%E6%9C%BA%E5%8C%96%E5%AD%A6%22%5D%2C%22abstractEN%22%3A%22Using%20urea%EF%BC%8C%20phthalic%20anhydride%2C%20sodium%20hydroxide%20and%20sodium%20hypochlorite%20(aq)%2C%20the%20procedure%20for%20the%20preparation%20of%20o-aminobenzoic%20acid%20is%20rearranged%20by%20Hoffmann%20and%20the%20product%20is%20subsequently%20esterified%20to%20prepare%20methyl%20o-aminobenzoate%22%2C%22abstract%22%3A%22%E4%BD%BF%E7%94%A8%E8%84%B2%EF%BC%8C%E9%82%BB%E8%8B%AF%E4%BA%8C%E7%94%B2%E9%85%B8%E9%85%90%EF%BC%8C%E6%B0%A2%E6%B0%A7%E5%8C%96%E9%92%A0%E5%92%8C%E6%AC%A1%E6%B0%AF%E9%85%B8%E9%92%A0(aq)%EF%BC%8C%E9%80%9A%E8%BF%87%E9%9C%8D%E5%A4%AB%E6%9B%BC%E9%87%8D%E6%8E%92%E5%88%B6%E5%A4%87%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8%E7%9A%84%E6%93%8D%E4%BD%9C%E6%B5%81%E7%A8%8B%EF%BC%8C%E9%9A%8F%E5%90%8E%E5%B0%86%E4%BC%9A%E6%8A%8A%E4%BA%A7%E7%89%A9%E9%85%AF%E5%8C%96%E4%BB%A5%E5%88%B6%E5%A4%87%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8%E7%94%B2%E9%85%AF%EF%BC%8C%22%2C%22origin%22%3A0%2C%22authorInfos%22%3A%5B%5D%2C%22wordCount%22%3A452%2C%22source%22%3A%22article%22%2C%22sid%22%3A%22610odz%22%2C%22ip%22%3A%22672b0778cd0deffe1dfe6afe%22%2C%22port%22%3A%222834%22%2C%22addr%22%3A%22%E6%B1%9F%E8%8B%8F%22%2C%22atUsers%22%3A%5B%5D%2C%22__v%22%3A0%2C%22l%22%3A%22html%22%2C%22doi%22%3A%22%22%2C%22uidlm%22%3A%22%24uid%22%2C%22hash%22%3A%22sha256%3Aab3c9bfc96215698abcf522468e135b7ee484faedae1cd4983e06368ebd6999c%22%2C%22version%22%3A1%2C%22metadata%22%3A%5B%5D%2C%22funders%22%3A%5B%5D%2C%22id%22%3A%22901399%22%7D%2C%22editorUrl%22%3A%22%2Fcolumn%2Feditor%3Fsource%3Dcolumn%26aid%3D610odz%22%2C%22user%22%3A%7B%22_id%22%3A%2267273a372414d59f67860f87%22%2C%22destroyed%22%3Afalse%2C%22kcb%22%3A0%2C%22oldKcb%22%3A0%2C%22toc%22%3A%222024-11-03T08%3A54%3A15.876Z%22%2C%22xsf%22%3A0%2C%22tlv%22%3A%222026-05-30T11%3A35%3A00.868Z%22%2C%22disabledPostsCount%22%3A0%2C%22disabledThreadsCount%22%3A0%2C%22postCount%22%3A0%2C%22threadCount%22%3A0%2C%22recCount%22%3A0%2C%22toppedThreadsCount%22%3A0%2C%22digestThreadsCount%22%3A0%2C%22digestPostsCount%22%3A0%2C%22dailyLoginCount%22%3A36%2C%22violationCount%22%3A0%2C%22score%22%3A0.72%2C%22username%22%3A%22SAS%22%2C%22usernameLowerCase%22%3A%22sas%22%2C%22uid%22%3A%22105575%22%2C%22cart%22%3A%5B%5D%2C%22description%22%3A%22%22%2C%22color%22%3A%22%22%2C%22certs%22%3A%5B%22examinated%22%5D%2C%22hidden%22%3Afalse%2C%22volumeA%22%3Atrue%2C%22volumeB%22%3Atrue%2C%22online%22%3A%22%22%2C%22avatar%22%3A%22672756f033febfef5a529387%22%2C%22banner%22%3A%226727576014b53ca0d34e6e9e%22%2C%22homeBanner%22%3A%2267275799cd0deffe1de068f2%22%2C%22voteUpCount%22%3A0%2C%22voteDownCount%22%3A0%2C%22lastVisitSelf%22%3A%222024-11-03T08%3A54%3A15.905Z%22%2C%22__v%22%3A0%2C%22postSign%22%3A%22%22%2C%22volumeAD%22%3Atrue%2C%22grade%22%3A%7B%22postToForum%22%3A%7B%22countLimit%22%3A%7B%22unlimited%22%3Afalse%2C%22num%22%3A5%7D%2C%22timeLimit%22%3A%7B%22unlimited%22%3Afalse%2C%22num%22%3A5%7D%7D%2C%22postToThread%22%3A%7B%22countLimit%22%3A%7B%22unlimited%22%3Afalse%2C%22num%22%3A50%7D%2C%22timeLimit%22%3A%7B%22unlimited%22%3Afalse%2C%22num%22%3A1%7D%7D%2C%22_id%22%3A0%2C%22description%22%3A%22%E8%A7%81%E4%B9%A0%E6%9C%9F%22%2C%22color%22%3A%22%23aaaaaa%22%2C%22operationsId%22%3A%5B%5D%2C%22messagePersonCountLimit%22%3A2%2C%22messageCountLimit%22%3A500%2C%22postToThreadCountLimit%22%3A0%2C%22postToThreadTimeLimit%22%3A0%2C%22postToForumTimeLimit%22%3A0%2C%22postToForumCountLimit%22%3A0%2C%22displayName%22%3A%22%E5%AE%9E%E4%B9%A0%E4%BC%9A%E5%91%98%22%2C%22score%22%3A0%2C%22__v%22%3A0%2C%22id%22%3A%220%22%2C%22iconUrl%22%3A%22%2Fstatics%2Fgrade_icon%2Fv0l.png%22%7D%2C%22info%22%3A%7B%22certsName%22%3A%22%E8%BF%9B%E5%A3%AB%20%E6%9C%BA%E5%8F%8B%22%7D%2C%22id%22%3A%2267273a372414d59f67860f87%22%2C%22avatarUrl%22%3A%22%2Fa%2F672756f033febfef5a529387%3Fc%3DuserAvatar%22%7D%2C%22count%22%3A0%2C%22url%22%3A%22%2Farticle%2F610odz%22%2C%22documentResourceId%22%3A%22document-901399%22%2C%22vote%22%3Anull%7D%2C%22collectedCount%22%3A0%2C%22type%22%3A%22article%22%2C%22columnInfo%22%3A%7B%22userColumn%22%3Anull%2C%22columnPermission%22%3Afalse%2C%22column%22%3Anull%7D%2C%22isLastPage%22%3Atrue%7D

文号D897714

462

0

收藏

编辑文章

制备邻氨基苯甲酸

SAS2024-11-06 IP:江苏

中文摘要

使用脲，邻苯二甲酸酐，氢氧化钠和次氯酸钠(aq)，通过霍夫曼重排制备邻氨基苯甲酸的操作流程，随后将会把产物酯化以制备邻氨基苯甲酸甲酯，

Abstract

Using urea， phthalic anhydride, sodium hydroxide and sodium hypochlorite (aq), the procedure for the preparation of o-aminobenzoic acid is rearranged by Hoffmann and the product is subsequently esterified to prepare methyl o-aminobenzoate

关键词

有机化学

首先搭建反应装置

a.电热套，500ml的圆底烧瓶和通水冷凝管搭建成一个回流冷凝装置

b.称量反应物。74g邻苯二甲酸酐(0.5mol)与15g脲(0.25mol)混合后加入圆底烧瓶

c.冷凝管通入冷凝水后开始加热至混合物熔融，此时会放出二氧化碳，注意控温防止反应失控

ps:这是250ml的

d.当混合物膨胀后反应完成，冷却后加入100ml热水加热至沸腾过滤，干燥后即纯净的邻苯二甲酰亚胺(记为α)，共62g，产率84%

e.配置NaOH(aq)适量(共含有NaOH 33g)，加入所有的α，等待溶液澄清。

f.准备300mlNaClO(aq)冷却至5℃

g.搭建冰水浴冷却e的溶液随后慢慢滴入NaClO(aq)。此时发生霍夫曼重排。

反应液颜色变深，这是副反应。

同时生成CO₂放出

h.滴加完成后，加入稀硫酸调ph至4左右(注意CO₂放出)，即有棕色沉淀产生，抽滤获得邻氨基苯甲酸，产物应是无水的，作者用50%的EtOH重结晶了一次。产品干燥后30g，产率51%

(ps:作者将会用于合成邻氨基苯甲酸甲酯，故无需非常纯净)

0

全部只看作者

还没有人评论哦~~

全部只看作者

想参与大家的讨论？现在就登录或者注册。

SAS

实习会员

进士机友

文章

0

回复

0

学术分

0

2024/11/03注册，5个月3天前活动

暂无简介

主体类型：个人

所属领域：无

认证方式：手机号

IP归属地：江苏

名片私信

ID: {{ user.uid }}

{{ user.username }}

用户已注销

{{ user.info.certsName }}

{{ user.description }}

{{ format('YYYY/MM/DD', user.toc) }}注册，{{ fromNow(user.tlv) }}活动

{{ user.threadCount - user.disabledThreadsCount }}

{{ user.postCount - user.disabledPostsCount }}

学术分

{{ user.xsf }}

投诉或举报

加载中...

{{ tip }}

请选择违规类型：

{{ reason.type }}

空空如也

提交成功！

加载中...

回复

设为精选取消精选

评学术分

鼓励

通过审核

移动文章

加入收藏取消收藏

退修或删除

违规记录

投诉或举报

加入黑名单移除黑名单

查看IP

{{ format('YYYY/MM/DD HH:mm:ss', toc) }}

回复

加入收藏取消收藏